Chapter Twelve

Hallucinogens

Psychedelics

Facts About Hallucinogens

Hallucinogen

any drug that radically changes one’s mental state by distorting perception of reality to the point where hallucinations occur

AKA: Psychedelic or mind-expanding drugs

Hallucinogens

Wide variety of substances that differ in structure

range from wholly synthetic products to natural plant extracts

Hallucinogens

Examples

Mescaline can be manufactured synthetically or extracted from peyote cactus.

Psilocybin can be chemically produced or extracted from certain mushrooms.

Hallucinogens

Some hallucinogens are found in naturally occurring substances

morning glory seeds

jimson weed

nutmeg

mushrooms

*cannabis is often classified as a hallucinogen

General Effects

Effects depend on

the amount taken

the user’s past drug experience

the manner in which the drug is taken

the circumstances under which the drug is taken

Hallucinogens

Effects of hallucinogens and reaction differs from person to person.

range from ecstasy to terror

Emotional state varies during one episode.

Hallucinogens

Low doses cause wide range of effects depending on the properties of the drug and the user’s sensitivity.

Hallucinations are most likely to occur at high doses.

Hallucinogens

User may have different reactions to the same drug on different occasions.

pleasant one time and very disturbing or threatening the next

Probably due to the wide variations in composition and quality of illicit drugs.

Tolerance and Dependence

Regular use of hallucinogens such as LSD, mescaline, and psilocybin induces tolerance within a few days.

little or no effect is experienced even with high doses

Cross-tolerance develops among LSD, mescaline, psilocybin, and DMT.

Normal sensitivity usually returns after abstaining for several consecutive days.

Tolerance and Dependence

Chronic users may become psychologically dependent.

Hallucinogens do not appear to cause physical dependence

Withdrawal reactions have not be observed even after long-term use.

LSD

Manufactured from lysergic acid found in ergot, a fungus that grows on rye and other grains.

One of the most potent mood-altering chemicals.

Odorless, colorless, and tasteless

Sold on the streets in tablets, capsules, and occasionally in liquid form.

LSD

Usually taken orally but can be injected

often added to absorbent paper and divided into small decorated squares with each square representing one dose

LSD

The effects of high doses can last for 10 to 12 hours.

Tolerance develops rapidly.

LSD

Common street names

acid

trips

tabs

blotters

microdots

stars

purple mike

blue mike

superman

LSD

can take 20 to 60 minutes to take effect

resulting altered state of mind à "trip"

one trip can last from 4 to 12 hours depending on the amount of drug taken

LSD

Physical effects

increased blood pressure

dilated pupils

rapid heart rate

LSD

Other frequent side effects

muscular weakness

trembling

nausea

chills

hyperventilation

impaired motor skills and coordination

LSD

intense effects on perception, thought, and mood

user may experience several different emotions at one time or swing rapidly from one mood to another

hearing, smell and vision may be intensified or merged

sense of time and space may be affected

LSD

Diminishes user’s capacity to distinguish the boundaries between one object and another and differentiate between self and the environment.

LSD

Some users experience prolonged serious depression, anxiety, and even psychotic reactions.

LSD

Possible after-effect are "flashbacks".

Spontaneous recurrence of the sensations that occurred during a previous trip.

Can occur days, weeks, or even years after LSD use.

May be pleasant or severely disturbing.

Psilocybin

The active ingredient in the Psilocybe mexicana mushroom and some other mushroom species.

Psilocybin

Pure psiolcybin is a white crystalline substance.

Sold as crude mushroom preparation

capsule containing a powdered material of any color

Usually taken orally but can be injected.

Psilocybin

Effects are usually felt within 1/2 hour and last several hours.

Small doses may cause mental and physical relaxation, fatigue, detachment.

Psilocybin

Effects

Mood swings

Vivid perceptual distortion

Disrupted thought patterns

Intense preoccupation with trivial details

Users often report profound mystical or religious experiences.

Psilocybin

Larger doses can produce

dizziness

lightheadedness

abdominal discomfort

numbness of the tongue, lips, mouth

nausea

anxiety

shivering

Psilocybin

Marked changes in perception gradually develop and the user experiences effects similar to those of LSD.

DMT (dimethyltryptamine)

Synthetic chemical resembling psilocin

usually consumed along with marijuana

marijuana is soaked in solution of DMT, then dried and smoked in a pipe or as a cigarette

DMT

Effects

similar to those of LSD

begin almost immediately after ingestion

last approximately 30 to 60 minutes

DMT

anxiety reactions and panic states are more frequently associated with DMT than other hallucinogens

 

Morning Glory Seeds

The predominant active ingredient is chemically related to LSD but about 1/10 as potent.

Seeds are brown or black and can be eaten or ground.

Have little effect if eaten whole.

Morning Glory Seeds

If chewed, effects begin within 30 to 90 minutes and are similar to those of LSD.

Active ingredient, lysergic acid, can be extracted from the seeds and injected to produce a more intense, immediate experience.

Morning Glory Seeds

Packaged commercially and sold legally.

Often treated with insecticides, fungicides, and other chemicals and are poisonous if enough seeds are consumed.

Mescaline

Prepared from the peyote cactus

Heads or "buttons" of the cactus are dried, then sliced, chopped, or ground.

Can be synthesized as a powder and distributed in capsule or tablet form.

Mescaline

Usually taken orally

Can be inhaled by smoking ground peyote "buttons".

Can be injected but this is rare

considerably less potent than LSD

At low doses, onset of effects are slow and last from 1 to 18 hours.

Mescaline

Physical effects include

dilated pupils

higher body temperature

some muscular relaxation

nausea

vomiting

Mescaline

Common mental effects

euphoria

heightened sensory perception

visual hallucinations

perceived alterations of one’s body image

difficulty thinking

reports of mystical religious experiences are common

Mescaline

High doses cause

headache

dry skin

hypotension (low BP)

cardiac depression

slowing of respiratory rate